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Provectus starts compassionate use program for PV-10

Provectus Pharmaceuticals, Inc. (OTCBB: PVCT) expanded its compassionate use program for PV-10, making the agent, which is being developed as a therapeutic agent for a broad spectrum of cancers, available for select cancer patients in the United States. The program is already in progress in Australia, where it was initiated in June 2009. The program for PV-10 is being implemented under the FDA’s guidelines covering compassionate use of an investigational new drug. Read the release.

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Positive Palifosfamide Sarcoma Phase II Data from ZIOPHARM

ZIOPHARM Oncology, Inc. (Nasdaq: ZIOP) announced positive data from the multicenter randomized Phase II trial of palifosfamide (ZymafosTM, ZIO-201) treating patients with unresectable or metastatic soft tissue sarcoma. The analysis evaluated 62 patients treated as of the end of September, with 58 being analyzed. As a result of reaching a key efficacy milestone and following safety and efficacy data review by the Data Committee, sarcoma experts, and the Company’s Medical Advisory Board, made the decision Read More >

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Positive clinical trial results for Epeius

Epeius Biotechnologies Corporation announced results of its Rexin-G®  clinical trials. Administered as stand-alone therapy in late-stage cases of chemotherapy-resistant cancer, Rexin-G has shown benefits of remission in otherwise intractable metastatic cancers. Three recent cases of Stage IV metastatic cancer, namely (i) osteosarcoma, (ii) prostate cancer, and (iii) pancreas cancer, demonstrated that Rexin-G treatments alone led to clinical remission of disease in patients. Read the release.

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Locus Pharmaceuticals and Novartis enter into research collaboration

Locus Pharmaceuticals has entered into a discovery research collaboration with Novartis. Locus will collaborate with Novartis to discover novel chemotypes on targets of interest to Novartis’ select therapeutic areas.

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UsiRNA reduces tumor growth in vivo

MDRNA, Inc. (NASDAQ: MRNA) presented new in vivo data showing continued progress in the advancement of the Company’s oncology program. J. Michael French, President and CEO, reported that MDRNA’s UsiRNAs, delivered by the Company’s DiLA2 platform, down-regulated a previously “non-druggable” target with subsequent reductions in tumor growth in models of liver and bladder cancer via both systemic and local delivery.  Read the release.

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