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Fireside Chat: “Everything we knew in science 10 years ago is wrong.”

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The speed of scientific innovation these days is comparable to the PC innovation era of the 1980s, according to Robert Nelsen of ARCH Venture Partners at today’s BIO Investor Forum fireside chat. This is not to say that he feels investing in biopharma is a short term game. Robert urged the audience to “keep their faith” in good science and the “good ideas will percolate up” to yield innovative breakthroughs. Having played a significant role Read More >

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Stretching Your Dollar: Methods and Tools for Increasing the Productivity of Clinical Trials

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Recent Tufts data show clinical trials typically take nearly twice as long to complete enrollment as predicted at launch and 48% of trial sites miss enrollment targets.  Delays in trials shrink the returns from patent exclusivity and increase R&D costs.  New methods such as adaptive and batch trial designs, as well as explosive growth in digital tools, such as Apple’s ResearchKit, have transformed the trial design choices available.  These innovations, and others, provide new levers Read More >

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Fireside Chat: James Noble Says Go for IPO

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“Go for it,” was the parting advice James Noble, CEO and co-founder of Adaptimmune, had for pre-IPO biotech companies attending today’s BIO Investor Forum fireside chat. But, he said, be prepared for scrutiny from all sides… and mountains of paperwork. James co-founded Adaptimmune, a clinical-stage immunotherapy biopharmaceutical company, in July of 2008. At that time he was also part-time CEO of Immunocore, also a clinical-stage company engaged in T-cell receptor researches and develop. From this Read More >

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Biotech Policy Outlook at #BIF15: 21st Century Cures, IPR, TPP, and PDUFA VI

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To even the most casual observer, 2015 has been a big year in the biotech industry, particularly in Congress and in other venues wherein public policies that affect the sector take shape. Given the importance of the policy environment in determining how successful companies in our industry can be at delivering new cures and treatments to patients – and a return to the investors who finance their activities – we decided that a close look Read More >

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BIO Investor Forum Session Recap: Precision Medicine: Leveraging National Genomic Databases for Therapy Development (U.S., UK, Iceland)

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As the price point for full genome analysis falls through the $1,000 per person milestone, national efforts are ramping up for large studies that should enable much more personalized therapies.  This data should accelerate drug development by clarifying genetic targets and the most appropriate patient sub-groups for clinical trials. At the 14th Annual  BIO Investors Forum in San Francisco, a panel of precision medicine experts came together to share their perspectives on the current state Read More >

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