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CDC Report: C. diff Infections Associated with 29,000 Deaths per Year in US; Vaccines Could Provide Solution


Last month, the CDC released a new study on the impact of microbial super bug Clostridium difficile (C. diff) with some very disturbing findings. The study found that 29,000 deaths in the U.S. were associated with the bug in 2011, and nearly half a million Americans suffered infections. About half of those deaths, or 15,000, were estimated to be directly attributable to the infection. Elderly patients are most vulnerable to C. diff infections, with over Read More >

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The Value of Innovation to Save and Transform Lives


Patients have greater hope for cures to today’s most complex and challenging diseases thanks to modern specialty medicines, which allow doctors and patients to focus on prevention and avoid hospital care altogether. With the potential to save countless lives and improve so many more, today’s innovative life-enhancing medicines and therapies provide economic value far beyond their cost. The debate surrounding the value of modern specialty medicines focuses narrowly on one aspect – cost – while Read More >

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We Need Your Input: BIO Survey on Effective FDA-Sponsor Communication


BIO is surveying members and non-members on their interactions with the FDA during the various stages of drug development prior to submitting an NDA/BLA. The survey can be accessed here. Why is it important for you to share your feedback? In an increasingly competitive and fiscally-constrained environment, it is more important than ever for all stakeholders to work together to promote effective R&D for innovative medicines. In this BIO BuzzCenter video, Alnylam’s Dr. John Maraganore Read More >

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New PhRMA Report: A Decade of Innovation in Rare Diseases


Today, the Pharmaceutical Research and Manufacturers of America (PhRMA) released “A Decade of Innovation in Rare Diseases,” which highlights 10 years of progress in understanding rare diseases and drug development resulting in groundbreaking therapies. According to the report, more than 230 new medicines to treat rare or “orphan” diseases were approved by the U.S. Food and Drug Administration (FDA) in the last decade, and there are currently more than 450 orphan drugs in development. The Read More >

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Getting Ready for #RDD2015 (Rare Disease Day 2015)


Rare Disease Day is just around the corner on February 28th. R&D investment into rare disease research by venture capitalists was a major focus of BIO’s recent Venture Funding of Therapeutic Innovation between 2004-2013, available for download here. One of the more interesting findings in the study is the large increase of funding by venture capitalists for rare disease R&D over the past decade, as this chart illustrates: Over the last 10 years, there has Read More >

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