Category Archives: Health

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The Journey from the Bench to Bedside

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A partnership between a leading academic research center and a biologics company is aiming to develop new therapeutic opportunities Translational research enables therapies get to where they need to be – to the patient. The process is characterized by collaborative activity between university and company scientists. One recent example is the announcement of a three-year collaboration between MedImmune, the global biologics research and development arm of AstraZeneca, and the Clinical and Translational Science Institute (CTSI) Read More >

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Expand Investment in Basic Research Needed to Advance Medical Progress

Michael Coburn

In 2007, the Napier and Lane families struggled to find answers to their daughters’ developmental problems, which included impaired communication and socialization skills. Both of the girls had a disorder so rare that it subsequently became identified only by the name of the small fragment of chromosome 16 that was missing, namely “16p11.2 deletion syndrome.” Dan Pinkel and Joe Gray, researchers at the University of California, San Francisco developed microarray comparative genomic hybridization, a technology Read More >

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Delivering the Right Dose, Less Often

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Biologics are a growing area of drug development, including life-threatening and life-changing disorders such as cancer and rheumatoid arthritis. However, many biologics have short half-lives, and need to be dosed daily. To make them more convenient to use, as well as safer and more effective, researchers are developing delivery systems that keep the biologics in the body for longer, reducing the frequency of dosing. Swedish company Affibody is using the natural affinity of a naturally-occurring Read More >

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Acts of Support

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Because small biotechnology companies do not have product revenue, burdensome regulations have an outsized effect on them. One-size-fits-all compliance requirements – such as Section 404(b) of the Sarbanes-Oxley Act (SOX) – divert funds from the lab and slow the development process. We have already seen the benefits that positive legislative reform can have for capital formation for emerging growth companies (EGCs). The JOBS Act has led to a sea change in the regulatory landscape and Read More >

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US Public Organizations Leading Genomic Research, with Europe and Asia Catching Up

Gareth Williams  - Head Shot (March 2013) C High(2146527_1)

Since before the mapping of the human genome just over a decade ago, we have been applying our growing understanding the genome and associated –omes to medical and industrial uses. Thanks to this understanding, we now have the ability to pinpoint a specific genetic variation in a specific patient which can predict sensitivity to certain drugs. But where is innovation in genomics coming from? And where is it going? What roles are emerging markets playing? Read More >

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