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“Alz” Well That Ends Well: The Beta-Amyloid Debate in Alzheimer’s Research

alzheimers

Researchers and clinicians alike believe there is substantial evidence to support the hypothesis that Alzheimer’s disease (AD) may be caused by deposition of amyloid beta-peptide (Abeta) in plaques in brain tissue. But drugs targeted towards the beta-amyloid have met with significant setbacks challenging whether the target is, in fact, real. With several late stage drugs targeting beta-amyloid poised for market entry, a panel of opinion leaders in the treatment of Alzheimer’s and scientific industry specialists Read More >

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Fireside Chat with Moncef Slaoui, GlaxoSmithKline

Dr. Moncel Slaoui

Moncel Slaoui, chairman of research and development (R&D) at GlaxoSmithKline (GSK), opened the 2012 BIO CEO & Investor Conference with a Fireside Chat where he provided insight in to his company’s biopharma R&D strategy. “GSK has announced that our R&D budget is no more a percentage of sales. If you think about it, it doesn’t make sense,” Slaoui stated, “because, sales are a marker of R&D 10 and 15 years ago.” Right now, GSK has Read More >

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BIO Helps You Continuously Connect

Rob Wright

By Rob Wright, Life Science Leader As I perused a bunch of the show agendas I will be attending over the next several months, it occurred to me how helpful these shows are for helping connect me with people who make for interesting editorial. Depending upon the size of the show, this can be very easy or sometimes difficult. Last year’s BIO (Biotechnology Industry Organization) International Conference was held in in Washington D.C., and it Read More >

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The BioGENEius Challenge: Prarthana Dalal

prarthana

By Prarthana Dalal, 2011 International BioGENEius Challenge 1st Place Winner Project Title: Modeling of human non-deletional hereditary persistence of fetal hemoglobin (HPFH) conditions in β-globin locus transgenic mouse models: The -175 (T to C) and -195 (C to G) A-gamma globin gene point mutations Project Description: My project was focused on hemoglobingenetics and how sequence changes can effect fetal hemoglobin production in mouse models, which can be used to understand treatment mechanisms for sickle cell Read More >

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The BioGENEius Challenge: Priyen Patel

Priyen shaking hand

By Priyen Patel, 2011 U.S. National BioGENEius Media Award Winner Project Title: Over-the-Counter and In Your Water? The Most Effective Filtration of Pharmaceuticals Project Description: Research shows minute concentrations of drugs in 51 million Americans’ water, leading to tumors and reproductive problems in fish and slowing the growth of kidney cells in humans. I focused on filtering ibuprofen and acetaminophen and my results are: the water distiller (100% effective), the activated carbon filter and ion Read More >

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