Category Archives: Health

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Transforming Healthcare through Digital Innovation

samir-damani

Imagine being connected to expert health coaches on a daily basis instead of only at your annual doctor’s visit. What would it be like to be told on a real-time, continuous basis how many minutes of exercise at a specific heart rate was required, foods you needed to eat, and behaviors you needed to avoid in order to be feel better and be healthier? What if this information meant you could get off your hypertensive medications Read More >

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Precision Drugs for Bad Bugs

DavidwMartin

Awareness is high that antibiotic resistance is a critical problem, but many still don’t appreciate the role played by antibiotics themselves in accelerating this problem’s spread. Single antibiotics capable of killing multiple bacterial species – a class of drugs termed “broad spectrum” – have long been seen as a panacea and a cure for all bacterial infections. Today, essentially all marketed antibiotics kill multiple species of bacteria. Unfortunately bacteria that become resistant to a particular Read More >

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Reaction to the $1,000 Genome

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System promises to sequence tens of thousands of human whole genomes a year in a single laboratory. What do the first customers think? Life science technology company Illumina recently launched a sequencing platform that it claims will enable the $1,000 genome. The HiSeq X™ Ten Sequencing System comprises 10 ultra-high-throughput sequencers which together can sequence more than 18,000 genomes per year, making human whole-genome sequencing more affordable and accessible than ever before. The system builds Read More >

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Convention Attendees Make the Call on Expanded Access

Bioethics Panel

The BIO International Convention kicked off Monday with an interactive session organized by the BIO Board Standing Committee on Bioethics: The Bioethics of Drug Development—You Make the Call. Attendees engaged in a real-time polling exercise addressing the many difficult issues related to expanded access using a mock case study of a company – iCures – dealing with an expanded access request. Moderator Steve Usdin, Senior Editor, BioCentury, led the panel through challenging issues in drug Read More >

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Seek and Destroy

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Ubiquibodies combine the specificity of antibodies with the destruction signal of ubiquitinization. Stand by for targeted destruction of disease-causing proteins in the cell Proteins in a cell that are aged or otherwise damaged are recycled via the ubiquitin-proteasome pathway (UPP). The doomed protein is first tagged with a protein called ubiquitin, which acts like a molecular sign reading “destroy me”, and then broken down by the proteasome, which is the cell’s recycling center. This catabolism Read More >

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