Tag Archives: BIO 2014 Health

New Target for Alzheimer’s Disease

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Biotechnologists have developed a drug candidate that blocks production of diseasecausing neurotoxins in mouse models Reducing the concentration of cathepsin B using an enzyme inhibitor prevents the creation of the neurotoxic peptide, pyroglutamate-AB (pGlu-AB), which has been linked to the development of Alzheimer’s disease (AD). The candidate inhibitor drug, a cysteine protease inhibitor named E64d, was developed by scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and Read More >

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Making the Case for Personalized Medicine

Personalized-Medicine

Personalized medicine is the customization of healthcare. Already, a suite of molecular approaches is being used to tailor certain medical decisions, practice and products to the individual patient. For example, melanoma, leukemia and metastatic lung, breast and brain cancers can be routinely “molecularly diagnosed” and treated with medicines that target the specific genetic mutations. These represent a remarkable improvement over trial-and-error medicine. Other diagnostic tests use the patient’s DNA sequence to determine drug-metabolizing capabilities. This Read More >

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21st Century Cures: Accelerating the Discovery-Development-Delivery Cycle

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How can we give patients faster access to innovative treatments and cures? That’s the question the House Energy and Commerce Committee is asking our nation’s foremost medical experts and innovators through white papers, hearings, and roundtables in an initiative we call 21st Century Cures. Our collaboration includes everyone from the National Institutes of Health and the Food and Drug Administration to patients, researchers, health entrepreneurs, and other thought leaders. Through 21st Century Cures, our goal Read More >

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NIH, Patients and Industry Ramp Up to AMP-lify Innovation

Kay Holcomb

Speakers at Wednesday’s BIO 2014 Super Session – AMP-lifying Innovation: NIH, Patient Organizations & Leading Biopharma Firms Mobilize to Tackle Tough Diseases – discussed the new Accelerating Medicines Partnership (AMP) program, which is aimed at transforming the current model for developing new treatments by jointly identifying and validating promising biological targets of disease. AMP is a new venture among the NIH, several non-profit organizations and 10 biopharmaceutical companies focused on Alzheimer’s disease; type 2 diabetes Read More >

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Digital Health in a Mobile World

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Healthcare is shaping up to be an important area for all the big technology companies that focus on mobile devices. And that is pretty much all of them. When Sony sold off its VAIO computer division to Japan Industrial Partners earlier this year, among the reasons given were “drastic changes in the global PC industry”, and a need to “concentrate on … smartphones and tablets.” Over at Microsoft, new CEO Satya Nadella says we’ve entered Read More >

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