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Tag Archives: BIO Investor Forum
Positive Results in Plague Study
Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) announced results from a primate study involving the oral antibiotic Restanza(TM) (cethromycin) demonstrating statistical significance at a 90% survival rate against an inhaled lethal dose of plague. The study tested Restanza’s protective efficacy at various doses up to 64 mg/kg, where nine out of ten animals in the study that received a 14-day course of Restanza initiated within 24 hours after exposure to a lethal dose Read More >
Vical Licensee Completes Enrollment in Phase 3 Trial
Vical Incorporated (Nasdaq:VICL) licensee, sanofi-aventis, has completed enrollment in a 500-patient Phase 3 clinical trial of its angiogenesis therapy. The NV1FGF therapy contains DNA encoding Fibroblast Growth Factor 1 (FGF-1), a growth factor that stimulates the growth of blood vessels, and is intended to reduce the need for amputations in patients suffering from critical limb ischemia. The primary objective of the TAMARIS study is to demonstrate the superiority of NV1FGF treatment over placebo in the Read More >
Plexxikon Announces PLX4032 Phase I Clinical Trial Results
Plexxikon Inc. reports positive clinical data from a Phase 1 extension study of PLX4032 (RG7204) in metastatic melanoma patients. PLX4032 targets the BRAFV600E mutation that occurs in about 50 percent of melanomas and about eight percent of solid tumors. Tumor shrinkage has been observed in nearly all of the currently evaluable patients in the extension study, reflecting a 70 percent response rate. Plexxikon and Roche are co-developing PLX4032 under their 2006 license and collaboration agreement. Read More >
Peptimmune Collaborates with Walter Reed on Dengue Virus Vaccine
Peptimmune, Inc. has formed a collaboration with the Walter Reed Army Institute of Research and Naval Medical Research Center for the development of Dengue vaccines and point-of-care diagnostics. The goal of the R&D project is to evaluate the company’s Directed Expansion of Epitope Permutations (DEEP) technology to potentially design DENV-specific peptide copolymers. The results of this effort have the potential to provide insights into dengue immunity and advance the development of a protective vaccine. Read Read More >
Patient groups eager to speed cures
The 8th Annual BIO Investor Forum is attracting patient advocacy and venture philanthropy groups from across the country, who are interested in partnering to speed cures. Some of the participating organizations include: Fast Forward CureDuchenne The Leukemia & Lymphoma Society MDA Venture Philanthropy Epilepsy Therapy Project The Parkinson’s Institute These groups understand how critical it is for patient advocates, venture philanthropists, and biotech companies to work together to speed treatments and cures.




