Tag Archives: cancer

T-Cell Therapies: Best Bets in Pushing Down the Cost Curve and Prioritizing Cancer Targets

BIO Investor Forum

New approaches in cancer immunology are achieving promising early-stage results through novel techniques for arming the body’s own t-cells to have greater impact on reducing tumors and preventing the spread of disease. CAR-T methods that extract, reengineer, and reintroduce a given patient’s t-cells provide highly personalized therapy but may be difficult to scale up. The interleukin enhancement approach motivates existing t-cells to be more effective and may be easier to deliver but have less pervasive Read More >

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New PhRMA report: Nearly 800 Cancer Medicines in Development

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A new report from the Pharmaceutical Research and Manufacturers of America (PhRMA) shows that biopharma companies are currently developing nearly 800 new medicines and vaccines for cancer. “In recent decades, we have seen great progress in developing effective cancer treatments that help extend lives, improve quality of life and increase productivity,” said PhRMA President and CEO John J. Castellani. “Continued research has expanded our knowledge of how cancer develops and how to target medicines for Read More >

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The Hill: In War on Cancer, Patients at Risk of Becoming Commoditized

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Ted Okon, executive director of the Community Oncology Alliance, highlights the significant progress the medical community has made in the war on cancer but stresses the importance of access to care to improve and lengthen patients’ lives. “More Americans with cancer face longer life expectancies as a result of increased awareness among at-risk populations, better preventative care, early screenings, and new therapies,” writes Okon. “However, despite significant progress in the war on cancer, unnecessary access Read More >

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Mito What???

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Mitochondrial Disease: The Most Common Disease You’ve Probably Never Heard of… About 20 years ago, mitochondrial disease was virtually unheard of.  Just 10 years ago, it was considered rare. Today, according to NORD, a disease is considered rare when less than 200,000 people are affected.  Mitochondrial disease is not a single disease, but rather an entire umbrella of rare diseases.  For example, Alpers disease and Barth syndrome are very different and rare forms of mitochondrial Read More >

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Playing Detective With Checkpoint Therapies

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Three words are on the lips of everyone following new developments in cancer therapies: checkpoint inhibitor drugs. Simply put, investigators believe they have figured out a way to dismantle the mechanism used by cancer cells to stay hidden from T-cells, a type of specialized immune cell. CTLA-4 is a protein on the surface of T-cells that acts as an “off” switch for the sleuthing T-cells. It signals them to remain in a resting state, kind of like Read More >

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