Tag Archives: drug development

A Better Way to Make Unnatural Amino Acids Discovered by Yu

Make Unnatural Amino Acids

Certain amino acids that are not found in nature are highly sought after by pharmaceutical manufacturers. These “unnatural” amino acids have traditionally been very difficult to synthesize, so a new and improved technique for doing so is attracting a lot of attention. Amino acids are among the most basic components of living things. Long chains of them, translated from DNA, fold up to become proteins, some smaller groupings of amino acids form hormones, and a Read More >

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Making it Personal

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The “valley of death” between drug discovery and the development and provision of therapy is a huge issue in biotech. Recent news, however, highlights valiant entrepreneurs who look at the chasm and are building bridges to cross it. One of these is Ilan Ganot whose son, Eytani, was diagnosed with Duchenne muscular dystrophy (DMD) at the age of two years old. The ex-hedge fund banker at JPMorgan Chase & Co quit his job in London, Read More >

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Syringes for Clinical Trials

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Today’s pharmaceutical and biotechnology companies are under pressure to remain competitive. To do so, they require innovative approaches to manage drug development, particularly early development work. Any competitive advantage in the development process is highly prized – and one approach is to begin the development of the compound in a prefilled syringe earlier in the process, rather than later. Traditionally, biopharmaceutical companies have almost exclusively used vials in drug development. There are good reasons for Read More >

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Alliance Development Meets Animal Biotechnology

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On June 3rd, 2014, BIO hosted a briefing entitled “The Untapped Potential of Advanced Modeling: How Animal Biotech Speeds Drug Development” to showcase the growing field of biomedical applications through animal biotechnology. Panelists specifically highlighted opportunities for GE animal models of human disease to help patients with devastating diseases. The panel included three experts in the field: Danielle Kerkovich, PhD, the Principal Scientist of Beyond Batten Disease Foundation, John Swart, PhD, President of Exemplar Genetics, and Read More >

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Washington Post: Crowdsourcing Medical Decisions

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On Monday, Ariana Eunjung Cha wrote about the difficult ethical issue of Compassionate Use, which allows a patient access to an unapproved treatment when others with similar requests are denied access. Arthur Caplan, director of the division of medical ethics at New York University’s Langone Medical Center, describes it as a moral dilemma that could not be ‘more troubling and impossible-to-resolve’. In the article, Caplan asserts that ‘it’s best for the company to focus on getting the Read More >

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