Tag Archives: Medicine

New Target for Alzheimer’s Disease

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Biotechnologists have developed a drug candidate that blocks production of diseasecausing neurotoxins in mouse models Reducing the concentration of cathepsin B using an enzyme inhibitor prevents the creation of the neurotoxic peptide, pyroglutamate-AB (pGlu-AB), which has been linked to the development of Alzheimer’s disease (AD). The candidate inhibitor drug, a cysteine protease inhibitor named E64d, was developed by scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and Read More >

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Fighting Prostate Cancer with Immunotherapy

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Advaxis and UC San Francisco join forces to develop and test a range of novel constructs Prostate cancer is the second leading cause of cancer death in American men, behind lung cancer. According to the American Cancer Society, around 230,000 new cases of prostate cancer are diagnosed and 30,000 men die from the disease each year. Cancer immunotherapy offers one promising approach to combating the disease. The University of California, San Francisco, (UCSF) and biotechnology Read More >

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Making the Case for Personalized Medicine

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As lawmakers, industry, consumer groups and the general public debate the future of health care, personalized medicine continues to focus attention-with good reason. In a time of unprecedented scientific breakthroughs and technological advancements, personalized health care has the capacity to detect the onset of disease at its earliest stages, preempt the progression of disease, and, at the same time, increase the efficiency of the health care system by improving quality, accessibility, and affordability. With that Read More >

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Thinking About Printing in the 4th Dimension

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Three-dimensional (3D) printing is used to manufacture everything from guns to guitars—and even underwear. The next big thing could be 4D printing. This adds time to the mix by using smart materials that transform themselves into finished articles under different conditions. Some of the most powerful early applications of 4D may be in biotechnology and medicine. “Stents, compression structures and drug delivery mechanisms could be printed and programmed to transform themselves directly in situ,” explains Read More >

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The Arrival of Actionable Personalized Medicine

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The pace of implementation of next-generation sequencing (NGS) in a clinical context, which almost rivals the development of the technology over the past decade, is driving the cost of a full genome sequence down to just a few thousand dollars. Diagnostic companies and medical centers are now routinely offering comprehensive genome analysis, as evidenced by the recent report from Baylor College of Medicine in the New England Journal of Medicine on the first 250 patients Read More >

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