Tag Archives: Ubiquibodies

Seek and Destroy

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Ubiquibodies combine the specificity of antibodies with the destruction signal of ubiquitinization. Stand by for targeted destruction of disease-causing proteins in the cell Proteins in a cell that are aged or otherwise damaged are recycled via the ubiquitin-proteasome pathway (UPP). The doomed protein is first tagged with a protein called ubiquitin, which acts like a molecular sign reading “destroy me”, and then broken down by the proteasome, which is the cell’s recycling center. This catabolism Read More >

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